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Patent Eligibility, 2020 ed. is a single-volume treatise that focuses upon patent-eligibility in contrast to patentability. \"Patentability\" is generally thought of in terms of novelty, an \"inventive step,\" or nonobviousness. While these criteria are important, the underlying requirement for any invention to be \"patentable\" is it must be \"patent-eligible.\" This work focuses upon patent eligibility, including providing the historical evolution of the case law as well as the current issues in the crosshairs of those involved in inter partes challenges to patents. This comprehensive review of patent-eligibility includes: Eligibility requirements to be patented under 35 USC § 101 Patent-eligible invention patentability under 35 USC §§ 102, 103 and 112 Patent-eligibility opinion by the honorable Giles Sutherland Rich in In re Bergy Historical analysis of patent-eligibility cases from In re Bergy and Diamond v. Chakrabarty, through Ariosa Diagnostics, Inc. v. Sequenom, Inc. The impact of Le Roy v. Tatham on current Supreme Court case law Defensive protection patent strategy Diamond v. Diehr, narrow offensive “Diehr claim” strategy The Alice Corp. V. CLS Bank International view of patent-eligibility All Elements rule of Barret v. Hall A review of preemption and the challenges of allowing broad patent protection Computer and biotechnology related inventions, and more